How to use: Step 1: Before use, shake the dropper vigorously, until the bottom of the dropper is clear, to disperse Bacillus spores throughout the serum. Step 2: Apply 2-5 drops to hands first or directly to area, once daily, and gently massage and then pat into skin. Can be used on damp or dry skin. Step 3: For optimal results: apply after toner and before moisturizer.